hidden pixel

Importin Information

Importin is a type of protein that moves other protein molecules into the nucleus by binding to a specific recognition sequence, called the nuclear localization signal (NLS). Importin is classified as a karyopherin.[1][2]

Importin has two subunits, importin α and importin β. Of these, importin α binds to the NLS of the protein to be imported to the nucleus whereas importin β helps in the docking of the importin heterodimer-bound protein to the nuclear pore complex. The NLS-Importin α-Importin β trimer dissociates after binding to Ran GTP inside the nucleus.[3]

Human importin genes

References

  1. ^ http://big.mcw.edu/display.php/1053.html
  2. ^ Görlich D, Prehn S, Laskey RA, Hartmann E (1994). "Isolation of a protein that is essential for the first step of nuclear protein import". Cell 79 (5): 767–78. doi:10.1016/0092-8674(94)90067-1. PMID 8001116.
  3. ^ Mattaj IW, Englmeier L (1998). "Nucleocytoplasmic transport: the soluble phase". Annu. Rev. Biochem. 67: 265–306. doi:10.1146/annurev.biochem.67.1.265. PMID 9759490.

External links

This protein-related article is a stub. You can help Wikipedia by expanding it. · ·
· · Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
By group
SLC1–10
  • (4) bicarbonate transporter (SLC4A1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
SLC11–20
  • (13) human Na+-sulfate/carboxylate cotransporter (SLC13A1, SLC13A2, SLC13A3, SLC13A4, SLC13A5)
  • (15) proton oligopeptide cotransporter (SLC15A1, SLC15A2, SLC15A3, SLC15A4)
SLC21–30
  • (23) Na+-dependent ascorbic acid transporter (SLC23A1, SLC23A2, SLC23A3, SLC23A4)
SLC31–40
  • (32) vesicular inhibitory amino-acid transporter (SLC32A1)
  • (37) sugar-phosphate/phosphate exchanger (SLC37A1, SLC37A2, SLC37A3, SLC37A4)
  • (40) basolateral iron transporter (SLC40A1)
SLC41–48
  • (41) MgtE-like magnesium transporter (SLC41A1, SLC41A2, SLC41A3)
  • (43) Na+-independent, system-L like amino-acid transporter (SLC43A1, SLC43A2, SLC43A3)
  • (45) Putative sugar transporter (SLC45A1, SLC45A2, SLC54A3, SLC45A4)
  • (46) Folate transporter (SLC46A1, SLC46A2)
  • (48) Heme transporter
SLCO1–4
O1A2 · O1B1 · O1B3 · O2B1 · O431 · O4A1
Ion pumps
Symporter, Cotransporter Na+/K+/2Cl- - Na/Pi3 - Na+/Cl- - Na/glucose - Na+/I- - Cl-/K+ (4, 5)
Antiporter (exchanger) Na+/H+ - Na+/Ca2+ (Na+/(Ca2+-K+)) - Cl-/HCO3- (Band 3) - Cl-formate exchanger - Cl-oxalate exchanger
see also : , (, , , , , , ),

Categories:

 

The above information uses material from Wikipedia and is licensed under the GNU Free Documentation License.
Some facts may not have been fully verified for accuracy. [Disclaimers]
This page was last archived by our server on Tue Oct 18 11:15:10 2011.
Displaying this page or its contents does not use any Wikimedia Foundation's resources.
The owners of this site proudly support the Wikimedia Foundation.

More Information Results for "Importin"
[Hide]▼
'Importin' Images
'Importin' Definition

English

Importin
from: Wiktionary: importin,
Sat May 12 14:12:38 2012
[Hide]▲