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Phosphomevalonic Acid Information

Phosphomevalonic acid is an intermediate in the Mevalonate pathway.

Mevalonate pathway. (Phosphomevalonic acid labeled as "mevalonate-5-phosphate"
Cholesterol and steroid metabolic intermediates
Mevalonate pathway
to HMG-CoA Acetyl-CoA · Acetoacetyl-CoA · HMG-CoA
Ketone bodies Acetone · Acetoacetic acid · beta-Hydroxybutyric acid
to DMAPP Mevalonic acid · Phosphomevalonic acid · 5-Diphosphomevalonic acid · Isopentenyl pyrophosphate · Dimethylallyl pyrophosphate
Geranyl- Geranyl pyrophosphate · Geranylgeranyl pyrophosphate
Carotenoid Prephytoene diphosphate · Phytoene
Non-mevalonate pathway
DOXP · MEP · CDP-ME · CDP-MEP · MEcPP · HMB-PP · IPP · DMAPP
To Cholesterol

Farnesyl pyrophosphate · Squalene · 2,3-Oxidosqualene · Lanosterol

Lanosterol · Lathosterol · 7-Dehydrocholesterol · Cholesterol

Lanosterol · Zymosterol · 7-Dehydrodesmosterol · Desmosterol · Cholesterol
From Cholesterol (to steroids) 22R-Hydroxycholesterol · 20α,22R-Dihydroxycholesterol
Steroid hormones
Corticosteroids (C21 pregnane)
Mineralocorticoids Pregnenolone · Progesterone · Cortodoxone · Corticosterone · Aldosterone
Glucocorticoids

Pregnenolone · 17-Hydroxypregnenolone · 17-Hydroxyprogesterone · Cortisol

Cortisol · Cortisone
Sex steroids
Androgens (C19 androstane)

DHEA · Androstenedione/5-Androstenediol · Testosterone · Dihydrotestosterone

DHEA sulfate · Epitestosterone
Estrogens (C18 estrane) Estetrol · Estrone · Estradiol · Estriol
Nonhuman
Phytosterols Stigmasterol · Brassicasterol
Ergosterols Ergosterol · Ergocalciferol

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