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Retropharyngeal Abscess Information

Most commonly seen in infants and young children, retropharyngeal abscess (RPA) is an abscess located in the tissues in the back of the throat behind the posterior pharyngeal wall (the retropharyngeal space). Because RPA's typically occur in deep tissue, they are difficult to diagnose by physical examination alone. RPA is a relatively uncommon illness, and therefore may not receive early diagnosis in children presenting with stiff neck, malaise, difficulty swallowing, or other symptoms listed below. Early diagnosis is key, while a delay in diagnosis and treatment may lead to death. Parapharyngeal space communicates with retropharyngeal space and an infection of retropharyngeal space can pass down behind the oesophagus into mediastinum. [1] RPA's can also occur in adults of any age.

RPA can lead to airway obstruction or sepsis - both life-threatening emergencies.[2] Fatalities normally occur from patients not receiving treatment immediately and suffocating prior to knowing that anything serious was wrong.

Contents

Causes

RPA is usually caused by a bacterial infection originating from the nasopharynx, tonsils, sinuses, adenoids or middle ear. Any Upper Respiratory Infection (URI) can be a cause. RPA can also result from a direct infection due to penetrating injury or a foreign body.

Symptoms

Symptoms may include stiff neck (limited neck mobility or torticollis)[3], some form of palpable neck pain (may be in "front of the neck" or around the Adam's Apple), malaise, difficulty swallowing, fever, stridor, drooling, croupy cough or enlarged cervical lymph nodes. Any combination of these symptoms should arouse suspicion of RPA.

Treatment

RPA's frequently require surgical intervention. A tonsillectomy approach is typically used to access/drain the abscess, and the outcome is usually positive. Surgery is done without general anesthesia since there is risk of rupture of abscess during intubation for anesthesia. In complex cases, tracheotomy may be required to prevent upper airway obstruction caused by edema in the neck.

High dose of Intravenous antibiotics are required in order to control the infection and reduce the size of the abscess prior to surgery.

Chronic retropharyngeal abscess is usually secondary to tuberculosis and the patient needs to be started on anti tubercular therapy as soon as possible.

Diagnosis

CT is the definitive diagnostic test. [4]

X ray of the neck 80% of the time shows swelling of the retropharyngeal space. If the retropharyngeal space is more than half of the size of the C2 vertebra, it may indicate retropharyngeal abscess.[5]

References

  1. ^ John Grosso, MD, Charles M. Meyer, MD {http://archpedi.ama-assn.org/cgi/reprint/144/12/1349}
  2. ^ McLeod C, Stanley KA (January 2008). "Images in emergency medicine: retropharyngeal abscess". West J Emerg Med 9 (1): 55. PMC 2672230. PMID 19561707. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2672230.
  3. ^ Frances W. Craig, MD*, Jeff E. Schunk, MD "Retropharyngeal Abscess in Children: Clinical Presentation, Utility of Imaging, and Current Management"
  4. ^ Amal Mattu; Deepi Goyal; Barrett, Jeffrey W.; Joshua Broder; DeAngelis, Michael; Peter Deblieux; Gus M. Garmel; Richard Harrigan; David Karras; Anita L'Italien; David Manthey (2007). Emergency medicine: avoiding the pitfalls and improving the outcomes. Malden, Mass: Blackwell Pub./BMJ Books. pp. 50. ISBN 1-4051-4166-2.
  5. ^ Gary Frank; Samir S Shah; Marina Catallozzi; Lisa B Zaoutis (1 June 2005). The Philadelphia guide: inpatient pediatrics. Lippincott Williams & Wilkins. pp. 181–. ISBN 9781405104289. http://books.google.com/?id=dBMP4uxNFMYC&pg=PA181. Retrieved 26 May 2010.
Pathology of respiratory system (J, 460–519), respiratory diseases
Upper RT (including URTIs, Common cold)
Head sinuses: Sinusitis nose: Rhinitis (Vasomotor rhinitis, Atrophic rhinitis, Hay fever) · Nasal polyp · Rhinorrhea · nasal septum (Nasal septum deviation, Nasal septum perforation, Nasal septal hematoma) tonsil: Tonsillitis · Adenoid hypertrophy · Peritonsillar abscess
Neck pharynx: Pharyngitis (Strep throat) · Laryngopharyngeal reflux (LPR) · Retropharyngeal abscess larynx: Croup · Laryngitis · Laryngopharyngeal reflux (LPR) · Laryngospasm vocal folds: Laryngopharyngeal reflux (LPR) · Vocal fold nodule · Vocal cord paresis · Vocal cord dysfunction epiglottis: Epiglottitis trachea: Tracheitis · Tracheal stenosis
Lower RT/lung disease (including LRTIs)
Bronchial/ obstructive acute: Acute bronchitis chronic: COPD (Chronic bronchitis, Acute exacerbations of chronic bronchitis, Acute exacerbation of COPD, Emphysema) · Asthma (Status asthmaticus, Aspirin-induced, Exercise-induced) · Bronchiectasis unspecified: Bronchitis · Bronchiolitis (Bronchiolitis obliterans) · Diffuse panbronchiolitis
Interstitial/ restrictive (fibrosis)
External agents/ occupational lung disease Pneumoconiosis (Asbestosis, Baritosis, Bauxite fibrosis, Berylliosis, Caplan's syndrome, Chalicosis, Coalworker's pneumoconiosis, Siderosis, Silicosis, Talcosis, Byssinosis) Hypersensitivity pneumonitis (Bagassosis, Bird fancier's lung, Farmer's lung, Lycoperdonosis)
Other ARDS · Pulmonary edema · Löffler's syndrome/Eosinophilic pneumonia · Respiratory hypersensitivity (Allergic bronchopulmonary aspergillosis) Hamman-Rich syndrome · Idiopathic pulmonary fibrosis · Sarcoidosis
Obstructive or restrictive
Pneumonia/ pneumonitis
By pathogen Viral · Bacterial (Pneumococcal, Klebsiella) / Atypical bacterial (Mycoplasma, Legionnaires' disease, Chlamydiae) · Fungal (Pneumocystis) · Parasitic · noninfectious (Chemical/Mendelson's syndrome, Aspiration/Lipid)
By vector/route Community-acquired · Healthcare-associated · Hospital-acquired
By distribution Broncho- · Lobar
IIP UIP · DIP · BOOP-COP · NSIP · RB
Other Atelectasis · circulatory (Pulmonary hypertension, Pulmonary embolism) · Lung abscess
Pleural cavity/ mediastinum
Pleural disease Pleuritis/pleurisy Pneumothorax/Hemopneumothorax (Tension pneumothorax) Pleural effusion: Hemothorax · Hydrothorax · Chylothorax · Empyema/pyothorax · Malignant Fibrothorax
Mediastinal disease Mediastinitis · Mediastinal emphysema
Other/general Respiratory failure · Influenza · SARS · Idiopathic pulmonary haemosiderosis · Pulmonary alveolar proteinosis

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