hidden pixel

Tonofibril Information

Tonofibrils are cytoplasmic protein structures in epithelial tissues[1] that converge at desmosomes and hemidesmosomes.

Tonofilaments are also associated with desmosomes (macula adherens), anchoring them to the cytoskeleton.

Composition

They are made of keratin (a type of intermediate filament in the cytoskeleton) tonofilaments.[2] Tonofilaments are keratin intermediate filaments that make up tonofibrils in epithelial tissue.

The protein filaggrin is believed to have an important role in holding them together as tonofibrils.

References

  1. ^ "tonofibril" at Dorland's Medical Dictionary
  2. ^ Yoon KH, Yoon M, Moir RD, Khuon S, Flitney FW, Goldman RD (April 2001). "Insights into the dynamic properties of keratin intermediate filaments in living epithelial cells". J. Cell Biol. 153 (3): 503–16. doi:10.1083/jcb.153.3.503. PMC 2190576. PMID 11331302. http://www.jcb.org/cgi/pmidlookup?view=long&pmid=11331302.

External links

This cell biology article is a stub. You can help Wikipedia by expanding it. · ·
· · Protein: scleroproteins
Extracellular matrix
Collagen
Fibril forming type I (COL1A1, COL1A2) · type II (COL2A1) · type III · type V (COL5A1, COL5A2, COL5A3) · COL24A1 · COL26A1
Other

FACIT: type IX (COL9A1, COL9A2, COL9A3) · type XII (COL12A1) · COL14A1 · COL16A1 · COL19A1 · COL20A1 · COL21A1 · COL22A1

basement membrane: type IV (COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6)

multiplexin: COL15A1 · type XVIII (COL18A1, Endostatin)

transmembrane: COL13A1 · COL17A1 · COL23A1 · COL25A1

other: type VI (COL6A1, COL6A2, COL6A3) · type VII (COL7A1) · type VIII (COL8A1, COL8A2) · type X (COL10A1) · type XI (COL11A1, COL11A2) · COL27A1 · COL28A1 · COL29A1
Enzymes Prolyl hydroxylase/Lysyl hydroxylase · Cartilage associated protein/Leprecan · ADAMTS2 · Procollagen peptidase · Lysyl oxidase
Tenascin Tenascin C · Tenascin X
Laminin alpha (LAMA1, LAMA2, LAMA3, LAMA4, LAMA5) · beta (LAMB1, LAMB2, LAMB3, LAMB4) · gamma (LAMC1, LAMC2, LAMC3)
Other ALCAM · Elastin (Tropoelastin) · Vitronectin · FRAS1 · FREM2 · Decorin · FAM20C · ECM1 · Matrix gla protein · Tectorin (TECTA, TECTB)
Other Keratin/Cytokeratin · Gelatin · Reticulin · Cartilage oligomeric matrix protein
see also : BY STRUCTURE: , (, , ),
· · Proteins of the cytoskeleton
Human
Microfilaments (ABPs)
Myofilament
Actins A1, A2, B, C1, G1, G2
Myosins I (MYO1A, MYO1B, MYO1C, MYO1D, MYO1E, MYO1F, MYO1G, MYO1H) · II (MYH1, MYH2, MYH3, MYH4, MYH6, MYH7, MYH7B, MYH8, MYH9, MYH10, MYH11, MYH13, MYH14, MYH15, MYH16) · III (MYO3A, MYO3B) · V (MYO5A, MYO5B, MYO5C) · VI (MYO6) · VII (MYO7A, MYO7B) · IX (MYO9A, MYO9B) · X (MYO10) · XV (MYO15A) · XVIII (MYO18A, MYO18B) · LC (MYL1, MYL2, MYL3, MYL4, MYL5, MYL6, MYL6B, MYL7, MYL9, MYLIP, MYLK, MYLK2, MYLL1)
Other

Tropomodulin (1, 2, 3, 4) · Troponin (T 1 2 3, C 1 2, I 1 2 3) · Tropomyosin (1, 2, 3, 4)

Actinin (1, 2, 3, 4) · Arp2/3 complex · actin depolymerizing factors (Cofilin (1, 2) · Destrin) · Gelsolin · Profilin (1, 2) · Titin
Other Wiskott-Aldrich syndrome protein · Fibrillin · Filamin (FLNA, FLNB, FLNC) · Espin · TRIOBP
IFs
Type 1/2 (Keratin, Cytokeratin)
Epithelial keratins (soft alpha-keratins)

type I/chromosome 17 (10, 12, 13, 14, 15, 16, 17, 19, 20) · chromosome 12 (18) · none (21)

type II/chromosome 12 (1, 2A, 3, 4, 5, 6A, 6B, 7, 8, 9)
Hair keratins (hard alpha-keratins)

type I/chromosome 17 (31, 32, 33A, 33B, 34, 35, 36, 37, 38)

type II/chromosome 12 (81, 82, 83, 84, 85, 86)
Ungrouped alpha

chromosome 17 (23, 24, 25, 26, 27, 28, 39, 40)

chromosome 12 (71, 72, 73, 74, 75, 76, 77, 78, 79, 80)
Not alpha Beta-keratin
Type 3 Desmin, GFAP, Peripherin, Vimentin
Type 4 Internexin, Nestin, Neurofilament (NEFL, NEFM, NEFH), Synemin, Syncoilin
Type 5 Lamin A, B
Microtubules/ MAPs
Kinesins KIF1A, KIF1B, KIF2A, KIF2C, KIF3B, KIF3C, KIF4A, KIF4B, KIF5A, KIF5B, KIF5C, KIF6, KIF7, KIF9, KIF11, KIF12, KIF13A, KIF13B, KIF14, KIF15, KIF16B, KIF17, KIF18A, KIF18B, KIF19, KIF20A, KIF20B, KIF21A, KIF21B, KIF22, KIF23, KIF24, KIF25, KIF26A, KIF26B, KIF27, KIFC1, KIFC2, KIFC3
Dyneins

axonemal: DNAH1, DNAH2, DNAH3, DNAH5, DNAH6, DNAH7, DNAH8, DNAH9, DNAH10, DNAH11, DNAH12, DNAH13, DNAH14, DNAH17, DNAI1, DNAI2, DNALI1, DNAL1, DNAL4

cytoplasmic: DYNC1H1, DYNC2H1, DYNC1I1, DYNC1I2, DYNC1LI1, DYNC1LI2, DYNC2LI1, DYNLL1, DYNLL2, DYNLRB1, DYNLRB2, DYNLT1, DYNLT3
Other Tau protein · Dynactin (DCTN1) · Tubulins (TUBA1A, TUBA1B, TUBA1C, TUBA3C, TUBA3D, TUBA3E, TUBA4A, TUBA8) · Stathmin · Tektin (TEKT1, TEKT2, TEKT3, TEKT4, TEKT5) · Dynamin (DNM1, DNM2, DNM3)
Catenins Alpha catenin · Beta catenin (APC) · Plakoglobin (gamma catenin) · Delta catenin · GAN
Membrane Dystrophin (Dystroglycan) · Utrophin · Ankyrin (ANK1, ANK2, ANK3) · Spectrin (SPTA1, SPTAN1, SPTB, SPTBN1, SPTBN2, SPTBN4, SPTBN5)
Other plakin (Desmoplakin, Plectin) · Talin (TLN1) · Vinculin · Plakophilin (PKP1, PKP2)
Nonhuman Major sperm proteins · Prokaryotic cytoskeleton (Crescentin, FtsZ, MreB)
see also : edmb (), (), , , , ()
· · Histology: Epithelial proteins (TH H1.00.01.1)
Lateral/cell-cell

Cell adhesion molecules: Adherens junction (Cadherin) · Desmosome (Desmoglein)

Ion channels: Gap junction/Connexon (Connexin)

Cytoskeleton: Desmosome (Desmoplakin, Plakoglobin, Tonofibril)

other membrane proteins: Tight junction (Claudin, Occludin, MARVELD2)
Basal/cell-matrix Basal lamina · Hemidesmosome/Tonofibril · Focal adhesion · Costamere
Apical Cilia/Kinocilium · Microvilli/Stereocilia (STRC)
: edmb (), (), , , , ()

Categories:

 

The above information uses material from Wikipedia and is licensed under the GNU Free Documentation License.
Some facts may not have been fully verified for accuracy. [Disclaimers]
This page was last archived by our server on Tue Dec 13 00:41:56 2011.
Displaying this page or its contents does not use any Wikimedia Foundation's resources.
The owners of this site proudly support the Wikimedia Foundation.

More Information Results for "Tonofibril"
[Hide]▼
'Tonofibril' Images
[Hide]▲